Cochlear Synaptopathy Changes Sound-Evoked Activity Without Changing Spontaneous Discharge in the Mouse Inferior Colliculus

Tinnitus and hyperacusis are life-disrupting perceptual abnormalities that are often preceded by acoustic overexposure. Animal models of overexposure have suggested a link between these phenomena and neural hyperactivity, i.e., elevated spontaneous rates (SRs) and sound-evoked responses. Prior work...

Full description

Bibliographic Details
Main Authors: Luke A. Shaheen, M. Charles Liberman
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnsys.2018.00059/full