Gene-Expression Analysis Identifies IGFBP2 Dysregulation in Dental Pulp Cells From Human Cleidocranial Dysplasia

Gene-Expression Analysis Identifies IGFBP2 Dysregulation in Dental Pulp Cells From Human Cleidocranial Dysplasia

Cleidocranial dysplasia (CCD) is an autosomal dominant disorder affecting osteoblast differentiation, chondrocyte maturation, skeletal morphogenesis, and tooth formation. Dental phenotype in CCD include over-retained primary teeth, failed eruption of permanent teeth, and supernumerary teeth. The und...

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Bibliographic Details
Main Authors: Stephen L. Greene, Olga Mamaeva, David K. Crossman, Changming Lu, Mary MacDougall
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Genetics
Subjects:
cleidocranial dysplasia
RUNX2
IGFBP2
IGF
dentinogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00178/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00178/full

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