Reduced blood brain barrier breakdown in P-selectin deficient mice following transient ischemic stroke: a future therapeutic target for treatment of stroke

<p>Abstract</p> <p>Background</p> <p>The link between early blood- brain barrier (BBB) breakdown and endothelial cell activation in acute stroke remain poorly defined. We hypothesized that P-selectin, a mediator of the early phase of leukocyte recruitment in acute ische...

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Bibliographic Details
Main Authors: Petterson Jodie, Muller Robert N, Kaur Jaspreet, Rushforth David, Tuor Ursula I, Jin Albert Y, Boutry Sébastien, Barber Philip A
Format: Article
Language:English
Published: BMC 2010-02-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/11/12