Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation

Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation

Clostridium difficile is currently the leading cause of nosocomial infection. Antibiotics remain the first-line therapy for C. difficile-associated diseases (CDAD), despite the risks of resistance promotion and further gut microbiota perturbation. Notably, the abundance of Bacteroides fragilis was r...

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Bibliographic Details
Main Authors: Huimin Deng, Siqi Yang, Yucheng Zhang, Kai Qian, Zhaohui Zhang, Yangyang Liu, Ye Wang, Yang Bai, Hongying Fan, Xinmei Zhao, Fachao Zhi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
Subjects:
next-generation probiotic
gut barrier
gut microbiota
Clostridium difficile
commensal bacteria
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02976/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02976/full

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