New Crystal Forms for Biologically Active Compounds. Part 2: Anastrozole as N-Substituted 1,2,4-Triazole in Halogen Bonding and Lp-π Interactions with 1,4-Diiodotetrafluorobenzene

For an active pharmaceutical ingredient, it is important to stabilize its specific crystal polymorph. If the potential interconversion of various polymorphs is not carefully controlled, it may lead to deterioration of the drug’s physicochemical profile and, ultimately, its therapeutic efficacy. The...

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Bibliographic Details
Main Authors: Mariya A. Kryukova, Alexander V. Sapegin, Alexander S. Novikov, Mikhail Krasavin, Daniil M. Ivanov
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Crystals
Subjects:
DFT
Online Access:https://www.mdpi.com/2073-4352/10/5/371