The role of cGAS-STING signalling in liver diseasesKey points

The role of cGAS-STING signalling in liver diseasesKey points

Summary: The recently identified novel cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) activates the downstream adaptor protein stimulator of interferon genes (STING) by catalysing the synthesis of cyclic GMP-AMP. This in turn initiates an innate immune response through the release of various cy...

Full description

Bibliographic Details
Main Authors: Ruihan Chen, Jiamin Du, Hong Zhu, Qi Ling
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:JHEP Reports
Subjects:
cGAS-STING signalling
innate immune response
viral hepatitis
nonalcoholic fatty liver disease
liver injury
hepatocellular carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555921001002

Internet

http://www.sciencedirect.com/science/article/pii/S2589555921001002

Similar Items