The role of cGAS-STING signalling in liver diseasesKey points
Summary: The recently identified novel cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) activates the downstream adaptor protein stimulator of interferon genes (STING) by catalysing the synthesis of cyclic GMP-AMP. This in turn initiates an innate immune response through the release of various cy...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-10-01
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Series: | JHEP Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589555921001002 |