The role of cGAS-STING signalling in liver diseasesKey points

The role of cGAS-STING signalling in liver diseasesKey points

Summary: The recently identified novel cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) activates the downstream adaptor protein stimulator of interferon genes (STING) by catalysing the synthesis of cyclic GMP-AMP. This in turn initiates an innate immune response through the release of various cy...

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Bibliographic Details
Main Authors:	Ruihan Chen, Jiamin Du, Hong Zhu, Qi Ling
Format:	Article
Language:	English
Published:	Elsevier 2021-10-01
Series:	JHEP Reports
Subjects:	cGAS-STING signalling innate immune response viral hepatitis nonalcoholic fatty liver disease liver injury hepatocellular carcinoma
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589555921001002

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