TRIF Differentially Regulates Hepatic Steatosis and Inflammation/Fibrosis in MiceSummary

TRIF Differentially Regulates Hepatic Steatosis and Inflammation/Fibrosis in MiceSummary

Background & Aims: Toll-like receptor 4 (TLR4) signaling is activated through 2 adaptor proteins: MyD88 and TIR-domain containing adaptor-inducing interferon-β (TRIF). TLR4 and MyD88 are crucial in nonalcoholic steatohepatitis (NASH) and fibrosis. However, the role of TRIF in TLR4-mediated NAS...

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Bibliographic Details
Main Authors: Ling Yang, Kouichi Miura, Bi Zhang, Hiroshi Matsushita, Yoon Mee Yang, Shuang Liang, Jingyi Song, Yoon Seok Roh, Ekihiro Seki
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X17300036

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http://www.sciencedirect.com/science/article/pii/S2352345X17300036

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