Exploration of Mechanochemical Activation in Solid-State Fluoro-Grignard Reactions

Owing to the strength of the C−F bond, the ‘direct’ preparation of Grignard reagents, i.e., the interaction of elemental magnesium with an organic halide, typically in an ethereal solvent, fails for bulk magnesium and organofluorine compounds. Previously described mecha...

Full description

Bibliographic Details
Main Authors: Isaiah R. Speight, Timothy P. Hanusa
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/3/570