Unilateral Nephrectomy Stimulates ERK and Is Associated With Enhanced Na Transport

Unilateral Nephrectomy Stimulates ERK and Is Associated With Enhanced Na Transport

Nephron loss initiates compensatory hemodynamic and cellular effects on the remaining nephrons. Increases in single nephron glomerular filtration rate and tubular flow rate exert higher fluid shear stress (FSS) on tubules. In principal cell (PC) culture models FSS induces ERK, and ERK is implicated...

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Bibliographic Details
Main Authors: Robert Repetti, Nomrota Majumder, Karin Carneiro De Oliveira, Jennifer Meth, Tenzin Yangchen, Mukut Sharma, Tarak Srivastava, Rajeev Rohatgi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Physiology
Subjects:
nephrectomy
sodium transport
mitogen activated protein kinase
cortical collecting duct
electrophysiology
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.583453/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.583453/full

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