Colchicine Alleviates Cholesterol Crystal-Induced Endothelial Cell Pyroptosis through Activating AMPK/SIRT1 Pathway

Cholesterol crystal- (CC-) induced endothelial cell inflammation and pyroptosis play an important role in the development of cardiovascular diseases, especially in atherosclerosis (AS). Increasing evidence suggests that cholesterol crystals are known to be a pivotal pathological marker of atheroscle...

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Bibliographic Details
Main Authors: Mengyue Yang, Hang Lv, Qi Liu, Lu Zhang, Ruoxi Zhang, Xingtao Huang, Xuedong Wang, Baihe Han, Shenglong Hou, Dandan Liu, Gang Wang, Jingbo Hou, Bo Yu
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/9173530