Multinuclear MRI to disentangle intracellular sodium concentration and extracellular volume fraction in breast cancer

Abstract The purpose of this work was to develop a novel method to disentangle the intra- and extracellular components of the total sodium concentration (TSC) in breast cancer from a combination of proton ( $$^{1}$$ 1 H) and sodium ( $$^{23}\hbox {Na}$$ 23 Na ) magnetic resonance imaging (MRI) measu...

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Bibliographic Details
Main Authors: Carlotta Ianniello, Linda Moy, Justin Fogarty, Freya Schnabel, Sylvia Adams, Deborah Axelrod, Leon Axel, Ryan Brown, Guillaume Madelin
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84616-9