MINFLUX nanometer-scale 3D imaging and microsecond-range tracking on a common fluorescence microscope

Minimal photon fluxes (MINFLUX) has enabled molecule-scale resolution in fluorescence microscopy but this had not been shown in standard, broadly applicable microscopy platforms. Here the authors report a solution to allow normal fluorescence microscopy while also providing 1-3 nm 3D resolution.

Bibliographic Details
Main Authors: Roman Schmidt, Tobias Weihs, Christian A. Wurm, Isabelle Jansen, Jasmin Rehman, Steffen J. Sahl, Stefan W. Hell
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21652-z