Ultra-efficient sequencing of T Cell receptor repertoires reveals shared responses in muscle from patients with Myositis

Ultra-efficient sequencing of T Cell receptor repertoires reveals shared responses in muscle from patients with Myositis

Background: Myositis, or idiopathic inflammatory myopathy (IIM), is a group disorders of unknown etiology characterized by the inflammation of skeletal muscle. The role of T cells and their antigenic targets in IIM initiation and progression is poorly understood. T cell receptor (TCR) repertoire seq...

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Bibliographic Details
Main Authors: Janelle M. Montagne, Xuwen Alice Zheng, Iago Pinal-Fernandez, Jose C. Milisenda, Lisa Christopher-Stine, Thomas E. Lloyd, Andrew L. Mammen, H. Benjamin Larman
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:EBioMedicine
Subjects:
TCR repertoire
Myositis
Idiopathic Inflammatory myopathy
Autoimmunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420303480

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http://www.sciencedirect.com/science/article/pii/S2352396420303480

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