Glycosylation of immunoglobulin g: role of genetic and epigenetic influences.

Glycosylation of immunoglobulin g: role of genetic and epigenetic influences.

OBJECTIVE:To determine the extent to which genetic and epigenetic factors contribute to variations in glycosylation of immunoglobulin G (IgG) in humans. METHODS:76 N-glycan traits in circulating IgG were analyzed by UPLC in 220 monozygotic and 310 dizygotic twin pairs from TwinsUK. A classical twin...

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Bibliographic Details
Main Authors: Cristina Menni, Toma Keser, Massimo Mangino, Jordana T Bell, Idil Erte, Irena Akmačić, Frano Vučković, Maja Pučić Baković, Olga Gornik, Mark I McCarthy, Vlatka Zoldoš, Tim D Spector, Gordan Lauc, Ana M Valdes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3855797?pdf=render

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http://europepmc.org/articles/PMC3855797?pdf=render

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