Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

Summary: In vitro drug tests using patient-derived stem cell cultures offer opportunities to individually select efficacious treatments. Here, we provide a study that demonstrates that in vitro drug responses in rectal organoids from individual patients with cystic fibrosis (CF) correlate with chang...

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Bibliographic Details
Main Authors: Gitte Berkers, Peter van Mourik, Annelotte M. Vonk, Evelien Kruisselbrink, Johanna F. Dekkers, Karin M. de Winter-de Groot, Hubertus G.M. Arets, Rozemarijn E.P. Marck-van der Wilt, Jasper S. Dijkema, Maaike M. Vanderschuren, Roderick H.J. Houwen, Harry G.M. Heijerman, Eduard A. van de Graaf, Sjoerd G. Elias, Christof J. Majoor, Gerard H. Koppelman, Jolt Roukema, Marleen Bakker, Hettie M. Janssens, Renske van der Meer, Robert G.J. Vries, Hans C. Clevers, Hugo R. de Jonge, Jeffrey M. Beekman, Cornelis K. van der Ent
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471930097X

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http://www.sciencedirect.com/science/article/pii/S221112471930097X

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