Detection of cynomolgus monkey anti-protein XYZ antibody using immunocapture-LC/MS

Although enzyme-linked immunosorbent assays and electrochemiluminescence (ECL) immunoassays are the most widely used platform for ADA detection, they may be compromised by drug interference. We describe here an alternate, free of drug interference, immunocapture-LC/MS methodology for detecting anti-...

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Bibliographic Details
Main Authors: David Roos, Linzhi Chen, Rajeev Vesapogu, Cheikh Kane, Jeffrey Duggan, Stephen Norris
Format: Article
Language:English
Published: Betasciencepress Publishers 2016-10-01
Series:Journal of Applied Bioanalysis
Subjects:
Online Access:http://dx.doi.org/10.17145/jab.16.016