αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells
Integrins can regulate antigen-specific and innate immune receptor signalling, thereby affecting immune cell function. Here the authors show that avß3 integrin controls Toll-like receptor (TLR) signalling by regulating its trafficking to limit TLR-mediated B-cell proliferation and antibody productio...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms10917 |