Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via Gαi-protein-coupled receptors and the AKT pathway[S]

Bile acids are important regulatory molecules that can activate specific nuclear receptors and cell signaling pathways in the liver and gastrointestinal tract. In the current study, the chronic bile fistula (CBF) rat model and primary rat hepatocytes (PRH) were used to study the regulation of glucon...

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Bibliographic Details
Main Authors: Risheng Cao, Zhumei Xu Cronk, Weibin Zha, Lixin Sun, Xuan Wang, Youwen Fang, Elaine Studer, Huiping Zhou, William M. Pandak, Paul Dent, Gregorio Gil, Phillip B. Hylemon
Format: Article
Language:English
Published: Elsevier 2010-08-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520370590