A Tumor-Targeted Replicating Oncolytic Adenovirus Ad-TD-nsIL12 as a Promising Therapeutic Agent for Human Esophageal Squamous Cell Carcinoma

A Tumor-Targeted Replicating Oncolytic Adenovirus Ad-TD-nsIL12 as a Promising Therapeutic Agent for Human Esophageal Squamous Cell Carcinoma

Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers in China and existing therapies have been unable to significantly improve prognosis. Oncolytic adenoviruses (OAds) are novel promising anti-tumor drugs and have been evaluated in several cancers including ESCC. However, the...

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Bibliographic Details
Main Authors: Zifang Zhang, Chunyang Zhang, Jinxin Miao, Zhizhong Wang, Zhimin Wang, Zhenguo Cheng, Pengju Wang, Louisa S. Chard Dunmall, Nicholas R. Lemoine, Yaohe Wang
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
Ad-TD-nsIL12
antitumour efficacy
ESCC
oncolytic adenovirus
Syrian hamster model
Online Access:https://www.mdpi.com/2073-4409/9/11/2438

Internet

https://www.mdpi.com/2073-4409/9/11/2438

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