Division of labour between PP2A-B56 isoforms at the centromere and kinetochore

PP2A-B56 is a serine/threonine phosphatase complex that regulates several major mitotic processes, including sister chromatid cohesion, kinetochore-microtubule attachment and the spindle assembly checkpoint. We show here that these key functions are divided between different B56 isoforms that locali...

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Bibliographic Details
Main Authors: Giulia Vallardi, Lindsey A Allan, Lisa Crozier, Adrian T Saurin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/42619