A functional genome-wide in vivo screen identifies new regulators of signalling pathways during early Xenopus embryogenesis.

Embryonic development requires exquisite regulation of several essential processes, such as patterning of tissues and organs, cell fate decisions, and morphogenesis. Intriguingly, these diverse processes are controlled by only a handful of signalling pathways, and mis-regulation in one or more of th...

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Bibliographic Details
Main Authors: Siwei Zhang, Jingjing Li, Robert Lea, Enrique Amaya, Karel Dorey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24244509/?tool=EBI