Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain

Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain

Neurosphere formation is commonly used as a surrogate for neural stem cell (NSC) function but the relationship between neurosphere-initiating cells (NICs) and NSCs remains unclear. We prospectively identified, and isolated by flow cytometry, adult mouse lateral ventricle subventricular zone (SVZ) NI...

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Bibliographic Details
Main Authors: John K Mich, Robert AJ Signer, Daisuke Nakada, André Pineda, Rebecca J Burgess, Tou Yia Vue, Jane E Johnson, Sean J Morrison
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-05-01
Series:eLife
Subjects:
stem cell
forebrain
fate-mapping
prospective identification
Bmi-1
Online Access:https://elifesciences.org/articles/02669

Internet

https://elifesciences.org/articles/02669

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