Recellularization of decellularized lung scaffolds is enhanced by dynamic suspension culture.

Strategies are needed to improve repopulation of decellularized lung scaffolds with stromal and functional epithelial cells. We demonstrate that decellularized mouse lungs recellularized in a dynamic low fluid shear suspension bioreactor, termed the rotating wall vessel (RWV), contained more cells w...

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Bibliographic Details
Main Authors: Aurélie Crabbé, Yulong Liu, Shameema F Sarker, Nicholas R Bonenfant, Jennifer Barrila, Zachary D Borg, James J Lee, Daniel J Weiss, Cheryl A Nickerson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4427280?pdf=render