Arterial endothelium creates a permissive niche for expansion of human cord blood hematopoietic stem and progenitor cells

Arterial endothelium creates a permissive niche for expansion of human cord blood hematopoietic stem and progenitor cells

Abstract Background Although cord blood (CB) offers promise for treatment of patients with high-risk hematological malignancies and immune disorders, the limited numbers of hematopoietic stem cell (HSC)/progenitor cell in a CB unit and straitened circumstances in expanding ex vivo make it quite chal...

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Bibliographic Details
Main Authors: Huilin Li, Haiyun Pei, Sihan Wang, Bowen Zhang, Zeng Fan, Yiming Liu, Xiaoyan Xie, Zhou Yang, Lei Xu, Yali Jia, Yun Bai, Yi Han, Lin Chen, Lijuan He, Xue Nan, Wen Yue, Xuetao Pei
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Arterial endothelial cells
Hematopoietic stem and progenitor cells
Expansion
Niche
Transplantation
Online Access:http://link.springer.com/article/10.1186/s13287-020-01880-8

Internet

http://link.springer.com/article/10.1186/s13287-020-01880-8

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