Identification of an IL-22-Dependent Gene Signature as a Pharmacodynamic Biomarker

Identification of an IL-22-Dependent Gene Signature as a Pharmacodynamic Biomarker

Interleukin-22 (IL-22) plays a role in epithelial barrier function and repair, and may provide benefits in conditions like inflammatory bowel disease. However, limited human data are available to assess the clinical effect of IL-22 administration. This study used a human intestinal cell line to iden...

Full description

Bibliographic Details
Main Authors: Julie Rae, Jason Hackney, Kevin Huang, Mary Keir, Ann Herman
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
IL-22
pharmacodynamic biomarker
IL-1β
IBD
antimicrobial
epithelial repair
Online Access:https://www.mdpi.com/1422-0067/22/15/8205

Internet

https://www.mdpi.com/1422-0067/22/15/8205

Similar Items