The Role of Proteasomes in the Thymus

The thymus provides a microenvironment that supports the generation and selection of T cells. Cortical thymic epithelial cells (cTECs) and medullary thymic epithelial cells (mTECs) are essential components of the thymic microenvironment and present MHC-associated self-antigens to developing thymocyt...

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Bibliographic Details
Main Authors: Melina Frantzeskakis, Yousuke Takahama, Izumi Ohigashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
TEC
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.646209/full