HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice

HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice

3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-(isopropoxymethyl)benzyl)benzene-1,2-diol (HPN) is a synthetic analogue of 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(ethoxymethyl)benzyl)benzene-1,2-diol (BPN), which is isolated from marine red alga Rhodomela confervoides with potent protein tyrosine phosphatase...

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Bibliographic Details
Main Authors: Jingya Li, Tao Wang, Luyong Zhang, Chao Guo, Bo Jiang, Shuju Guo, Dayong Shi
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Marine Drugs
Subjects:
bromophenol
protein tyrosine phosphatase 1B inhibitor
db/db mouse model
anti-diabetes properties
Online Access:http://www.mdpi.com/1660-3397/11/2/350

Internet

http://www.mdpi.com/1660-3397/11/2/350

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