RIM-Binding Protein 2 Promotes a Large Number of CaV1.3 Ca2+-Channels and Contributes to Fast Synaptic Vesicle Replenishment at Hair Cell Active Zones

RIM-Binding Protein 2 Promotes a Large Number of CaV1.3 Ca2+-Channels and Contributes to Fast Synaptic Vesicle Replenishment at Hair Cell Active Zones

Ribbon synapses of inner hair cells (IHCs) mediate high rates of synchronous exocytosis to indefatigably track the stimulating sound with sub-millisecond precision. The sophisticated molecular machinery of the inner hair cell active zone realizes this impressive performance by enabling a large numbe...

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Bibliographic Details
Main Authors: Stefanie Krinner, Tanvi Butola, SangYong Jung, Carolin Wichmann, Tobias Moser
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
RIM-BP
calcium
exocytosis
ribbon synapse
cochlea
electron microscopy
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00334/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00334/full

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