Bystander T-Cells Support Clonal T-Cell Activation by Controlling the Release of Dendritic Cell-Derived Immune-Stimulatory Extracellular Vesicles

Bystander T-Cells Support Clonal T-Cell Activation by Controlling the Release of Dendritic Cell-Derived Immune-Stimulatory Extracellular Vesicles

Extracellular vesicles (EV) that are released by immune cells are studied intensively for their functions in immune regulation and are scrutinized for their potential in human immunotherapy, for example against cancer. In our search for signals that stimulate the release of functional EV by dendriti...

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Bibliographic Details
Main Authors: Marthe F. S. Lindenbergh, Daniëlle G. J. Koerhuis, Ellen G. F. Borg, Esther M. van ‘t Veld, Tom A. P. Driedonks, Richard Wubbolts, Willem Stoorvogel, Marianne Boes
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
T-cells
extracellular vesicles/exosomes
HLA class I
antigen presentation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00448/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00448/full

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