Simultaneous assay for protease activities of hepatitis C virus and human immunodeficiency virus based on fluorescence detection

Abstract Hepatitis C virus protease (HCV-PR) and human immunodeficiency virus protease (HIV-PR) are important for virus maturation, and thus can be used as potential target molecules for the development of antiviral drugs for the treatment of viral infections. In this study, a novel assay was develo...

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Bibliographic Details
Main Authors: Tsutomu Kabashima, Keiko Tonooka, Makoto Takada, Masaaki Kai, Takayuki Shibata
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-45711-0