Inhalationally Administered Semifluorinated Alkanes (SFAs) as Drug Carriers in an Experimental Model of Acute Respiratory Distress Syndrome

Inhalationally Administered Semifluorinated Alkanes (SFAs) as Drug Carriers in an Experimental Model of Acute Respiratory Distress Syndrome

Aerosol therapy in patients suffering from acute respiratory distress syndrome (ARDS) has so far failed in improving patients’ outcomes. This might be because dependent lung areas cannot be reached by conventional aerosols. Due to their physicochemical properties, semifluorinated alkanes (SFAs) coul...

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Bibliographic Details
Main Authors: Matthias Otto, Jörg Krebs, Peter Welker, René Holm, Manfred Thiel, Luciano Gattinoni, Michael Quintel, Charalambos Tsagogiorgas
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pharmaceutics
Subjects:
fluorocarbons
aerosols
drug carriers
inhalation
respiratory distress syndrome
tissue distribution
Online Access:https://www.mdpi.com/1999-4923/13/3/431

Internet

https://www.mdpi.com/1999-4923/13/3/431

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