Sevoflurane Inhalation Accelerates the Long-Term Memory Consolidation via Small GTPase Overexpression in the Hippocampus of Mice in Adolescence.

Sevoflurane exposure impairs the long-term memory in neonates. Whether the exposure to animals in adolescence affects the memory, however, has been unclear. A small hydrolase enzyme of guanosine triphosphate (GTPase) rac1 plays a role in the F-actin dynamics related to the synaptic plasticity, as we...

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Bibliographic Details
Main Authors: Emi Nakamura, Hiroyuki Kinoshita, Guo-Gang Feng, Hisaki Hayashi, Maiko Satomoto, Motohiko Sato, Yoshihiro Fujiwara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5025001?pdf=render