Structure–Activity Relationship of HER2 Receptor Targeting Peptide and Its Derivatives in Targeted Tumor Therapy

Human epidermal growth factor (HER2) is a transmembrane tyrosine kinase receptor that is frequently overexpressed in breast cancer. Its increased level prognoses a poor patient outcome and a high mortality rate. Despite the widening spectrum of therapies that are becoming available to treat HER2+ br...

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Bibliographic Details
Main Authors: Beáta Biri-Kovács, Afrodité Adorján, Ildikó Szabó, Bálint Szeder, Szilvia Bősze, Gábor Mező
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/2/183