Variants in the IL17 pathway genes are associated with atopic asthma and atopy makers in a South American population

Abstract Background Asthma is a complex disorder with multiple phenotypes which can influence its severity and response to treatment. The TH17 lymphocytes producing IL-17A and IL17-F cytokines, may have a role on asthma inflammation. The aim of our study was to evaluate the association between genet...

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Bibliographic Details
Main Authors: Milca de J. Silva, Maria B. R. de Santana, Bruna R. Tosta, Roberta P. Espinheira, Neuza Maria Alcantara-Neves, Maurício L. Barreto, Camila Alexandrina Figueiredo, Ryan dos S. Costa
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13223-019-0340-7