Genetic Diagnostic Evaluation of Trio-Based Whole Exome Sequencing Among Children With Diagnosed or Suspected Autism Spectrum Disorder

Genetic Diagnostic Evaluation of Trio-Based Whole Exome Sequencing Among Children With Diagnosed or Suspected Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a group of clinically and genetically heterogeneous neurodevelopmental disorders. Recent tremendous advances in the whole exome sequencing (WES) enable rapid identification of variants associated with ASD including single nucleotide variations (SNVs) and indels. To...

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Bibliographic Details
Main Authors: Xiujuan Du, Xueren Gao, Xin Liu, Lixiao Shen, Kai Wang, Yanjie Fan, Yu Sun, Xiaomei Luo, Huili Liu, Lili Wang, Yu Wang, Zhuwen Gong, Jianguo Wang, Yongguo Yu, Fei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Genetics
Subjects:
autism spectrum disorder
whole exome sequencing
diagnostic yield
comorbidity
genetic etiology
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00594/full

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https://www.frontiersin.org/article/10.3389/fgene.2018.00594/full

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