Investigation of olfactory function in a Panx1 knock out mouse model

Investigation of olfactory function in a Panx1 knock out mouse model

Pannexin 1 (Panx1), the most extensively investigated member of a channel-forming protein family, is able to form pores conducting molecules up to 1.5 kDa, like ATP, upon activation. In the olfactory epithelium (OE), ATP modulates olfactory responsiveness and plays a role in proliferation and differ...

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Bibliographic Details
Main Authors: Stefan eKurtenbach, Paige eWhyte-Fagundes, Lian eGelis, Sarah eKurtenbach, Christiane eZoidl, Hanns eHatt, Valery I. Shestopalov, Georg eZoidl
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Behavior
Olfaction
pannexin
knock out mouse
extracellular ATP
Panx1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00266/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00266/full

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