Post-transcriptional regulation of BRCA1 through its coding sequence by the miR-15/107 group of miRNAs

MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression that act by degrading their RNA targets or by repressing the translation of messenger RNAs (mRNAs). Initially thought to primarily target the 3´ untranslated region (3´UTR) of mRNAs, miRNAs have since been shown to a...

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Bibliographic Details
Main Authors: Kevin eQuann, Yi eJing, Isidore eRigoutsos
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00242/full