Effect of intraoperative blood transfusion on Treg and FOXP3 in patients with digestive tract malignancies and different ABO blood types

Effect of intraoperative blood transfusion on Treg and FOXP3 in patients with digestive tract malignancies and different ABO blood types

Abstract Background Blood transfusion can cause immunosuppression and lead to worse outcomes in patients with digestive tract malignancies; however, the specific mechanism behind this is not completely understood. One theory is that increased numbers of regulatory CD3+CD4+CD25+FOXP3+ T cells (Tregs)...

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Bibliographic Details
Main Authors: Yajun Liu, Junzhi Sun, Yun Xia, Michael R. Lyaker, Jianshe Yu
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Anesthesiology
Subjects:
Blood transfusion
ABO blood group
Treg
FOXP3
Immunity
Digestive tract
Online Access:https://doi.org/10.1186/s12871-021-01330-9

Internet

https://doi.org/10.1186/s12871-021-01330-9

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