Two high-rate pentose-phosphate pathways in cancer cells

Abstract The relevant role of pentose phosphate pathway (PPP) in cancer metabolic reprogramming has been usually outlined by studying glucose-6-phosphate dehydrogenase (G6PD). However, recent evidence suggests an unexpected role for a less characterized PPP, triggered by hexose-6-phosphate dehydroge...

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Bibliographic Details
Main Authors: Vanessa Cossu, Marcella Bonanomi, Matteo Bauckneht, Silvia Ravera, Nicole Righi, Alberto Miceli, Silvia Morbelli, Anna Maria Orengo, Patrizia Piccioli, Silvia Bruno, Daniela Gaglio, Gianmario Sambuceti, Cecilia Marini
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79185-2