MnTE-2-PyP Attenuates TGF-β-Induced Epithelial-Mesenchymal Transition of Colorectal Cancer Cells by Inhibiting the Smad2/3 Signaling Pathway

MnTE-2-PyP Attenuates TGF-β-Induced Epithelial-Mesenchymal Transition of Colorectal Cancer Cells by Inhibiting the Smad2/3 Signaling Pathway

Background. As a key step in enhancing cancer cell invasion and metastasis, epithelial-mesenchymal transition (EMT) plays an important role in colorectal cancer progression. EMT is triggered by a variety of signaling pathways, among which the transforming growth factor β (TGF-β) signaling pathway ha...

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Bibliographic Details
Main Authors: Yu Yang, Pei Zhang, Ruicheng Yan, Qi Wang, Erhu Fang, Hongxue Wu, Shijun Li, Haiyan Tan, Xing Zhou, Xianxiong Ma, Yu Tang, Yongming Huang, Rui Deng, Ying Liu, Shilun Tong, Zhihua Wang, Rebecca E. Oberley-Deegan, Qiang Tong
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/8639791

Internet

http://dx.doi.org/10.1155/2019/8639791

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