MnTE-2-PyP Attenuates TGF-β-Induced Epithelial-Mesenchymal Transition of Colorectal Cancer Cells by Inhibiting the Smad2/3 Signaling Pathway
Background. As a key step in enhancing cancer cell invasion and metastasis, epithelial-mesenchymal transition (EMT) plays an important role in colorectal cancer progression. EMT is triggered by a variety of signaling pathways, among which the transforming growth factor β (TGF-β) signaling pathway ha...
Main Authors: | Yu Yang, Pei Zhang, Ruicheng Yan, Qi Wang, Erhu Fang, Hongxue Wu, Shijun Li, Haiyan Tan, Xing Zhou, Xianxiong Ma, Yu Tang, Yongming Huang, Rui Deng, Ying Liu, Shilun Tong, Zhihua Wang, Rebecca E. Oberley-Deegan, Qiang Tong |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2019-01-01
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Series: | Oxidative Medicine and Cellular Longevity |
Online Access: | http://dx.doi.org/10.1155/2019/8639791 |
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