BRCA1-Dependent Translational Regulation in Breast Cancer Cells.

BRCA1 (Breast Cancer 1) has been implicated in a number of cellular processes, including transcription regulation, DNA damage repair and protein ubiquitination. We previously demonstrated that BRCA1 interacts with PABP1 (Poly(A)-Binding Protein 1) and that BRCA1 modulates protein synthesis through t...

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Bibliographic Details
Main Authors: Estelle Dacheux, Anne Vincent, Nicolas Nazaret, Christophe Combet, Anne Wierinckx, Sylvie Mazoyer, Jean-Jacques Diaz, Joël Lachuer, Nicole Dalla Venezia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3689694?pdf=render