Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles

Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles

Extracellular vesicles (EVs) contain various cargo molecules, including RNAs and proteins. EVs, which include exosomes, are predicted to be suitable surrogates of their source cells for liquid biopsy to measure biomarkers. Several studies have performed qualitative comparisons of cargo molecule repe...

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Bibliographic Details
Main Authors: Kentaro Otake, Keiko Adachi‐Tominari, Hiroaki Nagai, Masayo Saito, Osamu Sano, Yoshihiko Hirozane, Hidehisa Iwata
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:FEBS Open Bio
Subjects:
biomarker
exosome
extracellular vesicle
induced pluripotent stem cell
motor neuron
RNA sequencing
Online Access:https://doi.org/10.1002/2211-5463.13059

Internet

https://doi.org/10.1002/2211-5463.13059

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