Development and Application of Extraction Methods for LC-MS Quantification of Microcystins in Liver Tissue

Development and Application of Extraction Methods for LC-MS Quantification of Microcystins in Liver Tissue

A method was developed to extract and quantify microcystins (MCs) from mouse liver with limits of quantification (LOQs) lower than previously reported. MCs were extracted from 40-mg liver samples using 85:15 (v:v) CH<sub>3</sub>CN:H<sub>2</sub>O containing 200 mM ZnSO<sub&...

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Bibliographic Details
Main Authors: David Baliu-Rodriguez, Daria Kucheriavaia, Dilrukshika S. W. Palagama, Apurva Lad, Grace M. O’Neill, Johnna A. Birbeck, David J. Kennedy, Steven T. Haller, Judy A. Westrick, Dragan Isailovic
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Toxins
Subjects:
microcystins
liver
quantification
solid-phase extraction
liquid chromatography-mass spectrometry
Online Access:https://www.mdpi.com/2072-6651/12/4/263

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https://www.mdpi.com/2072-6651/12/4/263

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