PDZ Binding Kinase/T-LAK Cell-Derived Protein Kinase Plays an Oncogenic Role and Promotes Immune Escape in Human Tumors

PDZ Binding Kinase/T-LAK Cell-Derived Protein Kinase Plays an Oncogenic Role and Promotes Immune Escape in Human Tumors

Background. PDZ binding kinase (PBK)/T-LAK cell-derived protein kinase (TOPK) is an important mitotic kinase that promotes tumor progression in some cancers. However, the pan-cancer analysis of PBK/TOPK and its role in tumor immunity are limited. Methods. The oncogenic and immune roles of PBK in var...

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Bibliographic Details
Main Authors: Tingting Feng, Yan Zhang, Sunbin Ling, Chenyang Xu, Yingqi Lyu, Tingting Lu, Xinyuan Liu, Lisha Ying, Yafeng Wan, Haijun Zhong, Dan Su
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2021/8892479

Internet

http://dx.doi.org/10.1155/2021/8892479

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