Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers

Abstract Background Links between colorectal cancer (CRC) and the gut microbiome have been established, but the specific microbial species and their role in carcinogenesis remain an active area of inquiry. Our understanding would be enhanced by better accounting for tumor subtype, microbial communit...

Full description

Bibliographic Details
Main Authors: Vanessa L. Hale, Patricio Jeraldo, Jun Chen, Michael Mundy, Janet Yao, Sambhawa Priya, Gary Keeney, Kelly Lyke, Jason Ridlon, Bryan A. White, Amy J. French, Stephen N. Thibodeau, Christian Diener, Osbaldo Resendis-Antonio, Jaime Gransee, Tumpa Dutta, Xuan-Mai Petterson, Jaeyun Sung, Ran Blekhman, Lisa Boardman, David Larson, Heidi Nelson, Nicholas Chia
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-018-0586-6