The Adaptive Immune Landscape of the Colorectal Adenoma–Carcinoma Sequence

The Adaptive Immune Landscape of the Colorectal Adenoma–Carcinoma Sequence

Background. The tumor immune microenvironment exerts a pivotal influence in tumor initiation and progression. The aim of this study was to analyze the immune context of sporadic and familial adenomatous polyposis (FAP) lesions along the colorectal adenoma–carcinoma sequence (ACS). Methods. We analyz...

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Bibliographic Details
Main Authors: João Augusto Freitas, Irene Gullo, Diogo Garcia, Sara Miranda, Louisa Spaans, Lídia Pinho, Joana Reis, Fabiana Sousa, Manuela Baptista, Carlos Resende, Dina Leitão, Cecília Durães, José Luis Costa, Fátima Carneiro, José Carlos Machado
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
colorectal adenoma
colorectal adenocarcinoma
familial adenomatous polyposis
APC germline alterations
tumor immune microenvironment
immunogenicity
Online Access:https://www.mdpi.com/1422-0067/22/18/9791

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https://www.mdpi.com/1422-0067/22/18/9791

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