THE EFFECTS OF GABA-ERGIC DRUGS ON NALOXONE-PRECIPITATED WITHDRAWAL SIGNS IN CHRONICALLYMORPHINE-TREATED MICE

1) Chronic administration of morphine hydrochloride in the drinking water of mice induced physical dependence. Jumping and diarrhea, two signs of withdrawal, were produced by intraperitoneal (IP) injection of naloxone."n2) Baclofen, bicuculline and picrotoxin decreased the number of mice&am...

Full description

Bibliographic Details
Main Authors: Ali Mahfouzi, Mohammad Reza Zarrindast
Format: Article
Language:English
Published: Tehran University of Medical Sciences 1994-06-01
Series:Acta Medica Iranica
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4983.pdf&manuscript_id=4983