Tigmint: correcting assembly errors using linked reads from large molecules

Tigmint: correcting assembly errors using linked reads from large molecules

Abstract Background Genome sequencing yields the sequence of many short snippets of DNA (reads) from a genome. Genome assembly attempts to reconstruct the original genome from which these reads were derived. This task is difficult due to gaps and errors in the sequencing data, repetitive sequence in...

Full description

Bibliographic Details
Main Authors: Shaun D. Jackman, Lauren Coombe, Justin Chu, Rene L. Warren, Benjamin P. Vandervalk, Sarah Yeo, Zhuyi Xue, Hamid Mohamadi, Joerg Bohlmann, Steven J.M. Jones, Inanc Birol
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Bioinformatics
Subjects:
Assembly correction
Genome scaffolding
Genome sequence assembly
10x Genomics Chromium
Linked reads
Online Access:http://link.springer.com/article/10.1186/s12859-018-2425-6

Internet

http://link.springer.com/article/10.1186/s12859-018-2425-6

Similar Items